Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism
Transcriptional dysregulation of the MYC oncogene is among the most frequent events in aggressive tumor cells, and this is generally accomplished by acquisition of a super-enhancer somewhere within the 2.8 Mb TAD where MYC resides. We find that these diverse cancer-specific super-enhancers, differin...
| Main Authors: | , , , , , , , |
|---|---|
| Other Authors: | |
| Format: | Article |
| Published: |
Elsevier
2018
|
| Online Access: | http://hdl.handle.net/1721.1/117042 https://orcid.org/0000-0002-0385-6176 https://orcid.org/0000-0003-0998-9882 https://orcid.org/0000-0001-6263-2423 https://orcid.org/0000-0001-8855-8647 |