Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes

Stem-cell-based therapies can potentially reverse organ dysfunction and diseases, but the removal of impaired tissue and activation of a program leading to organ regeneration pose major challenges. In mice, a 4-day fasting mimicking diet (FMD) induces a stepwise expression of Sox17 and Pdx-1, follow...

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Bibliographic Details
Main Authors: Villani, Valentina, Buono, Roberta, Wei, Min, Kumar, Sanjeev, Cohen, Pinchas, Sneddon, Julie B., Perin, Laura, Longo, Valter D., Cheng, Chia-Wei, Yilmaz, Omer
Other Authors: Koch Institute for Integrative Cancer Research at MIT
Format: Article
Published: Elsevier BV 2018
Online Access:http://hdl.handle.net/1721.1/117051
https://orcid.org/0000-0003-1088-923X
https://orcid.org/0000-0002-7577-4612