APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALL
Oncogenic driver mutations are those that provide a proliferative or survival advantage to neoplastic cells, resulting in clonal selection. Although most cancer-causing mutations have been detected in the protein-coding regions of the cancer genome; driver mutations have recently also been discovere...
Main Authors: | , , , , , , , , , , , , , , , |
---|---|
Other Authors: | |
Format: | Article |
Published: |
Nature Publishing Group
2018
|
Online Access: | http://hdl.handle.net/1721.1/117055 https://orcid.org/0000-0001-8855-8647 |