APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALL

APOBEC signature mutation generates an oncogenic enhancer that drives LMO1 expression in T-ALL

Oncogenic driver mutations are those that provide a proliferative or survival advantage to neoplastic cells, resulting in clonal selection. Although most cancer-causing mutations have been detected in the protein-coding regions of the cancer genome; driver mutations have recently also been discovere...

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Bibliographic Details
Main Authors: Li, Z, Abraham, B J, Berezovskaya, A, Farah, N, Liu, Y, Leon, T, Fielding, A, Tan, S H, Sanda, T, Weintraub, A S, Li, B, Shen, S, Zhang, J, Mansour, M R, Look, A T, Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/117055
https://orcid.org/0000-0001-8855-8647

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http://hdl.handle.net/1721.1/117055
https://orcid.org/0000-0001-8855-8647

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