Aneuploidy triggers a TFEB-mediated lysosomal stress response
Aneuploidy, defined as an alteration in chromosome number that is not a multiple of the haploid complement, severely affects cellular physiology. Changes in chromosome number lead to imbalances in cellular protein composition, thus disrupting cellular processes and causing proteins to misfold and ag...
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| Aineistotyyppi: | Artikkeli |
| Kieli: | en_US |
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Taylor & Francis
2018
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| Linkit: | http://hdl.handle.net/1721.1/117198 https://orcid.org/0000-0002-1501-6190 https://orcid.org/0000-0001-9837-0314 |