Nickel Sequestration by the Host-Defense Protein Human Calprotectin
The human innate immune protein calprotectin (CP, S100A8/S100A9 oligomer, calgranulin A/calgranulin B oligomer, MRP-8/MRP-14 oligomer) chelates a number of first-row transition metals, including Mn(II), Fe(II), and Zn(II), and can withhold these essential nutrients from microbes. Here we elucidate t...
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Format: | Article |
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American Chemical Society (ACS)
2018
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Online Access: | http://hdl.handle.net/1721.1/117267 https://orcid.org/0000-0002-6234-8155 https://orcid.org/0000-0001-5486-2755 https://orcid.org/0000-0002-6153-8803 |