Recurrent and functional regulatory mutations in breast cancer

Recurrent and functional regulatory mutations in breast cancer

Genomic analysis of tumours has led to the identification of hundreds of cancer genes on the basis of the presence of mutations in protein-coding regions. By contrast, much less is known about cancer-causing mutations in non-coding regions. Here we perform deep sequencing in 360 primary breast cance...

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Bibliographic Details
Main Authors: Parasuraman, Prasanna, Tiao, Grace, Kim, Jaegil, Taylor-Weiner, Amaro, Rodriguez-Cuevas, Sergio, Rosenberg, Mara, Hess, Julian, Stewart, Chip, Maruvka, Yosef E., Stojanov, Petar, Seepo, Sara, Cibulskis, Carrie, Tracy, Adam, Pugh, Trevor J., Lee, Jesse, Zheng, Zongli, Ellisen, Leif W., Iafrate, A. John, Boehm, Jesse S., Baselga, Jose, Hidalgo-Miranda, Alfredo, Shioda, Toshi, Bernards, Andre, Engreitz, Jesse Michael, Lander, Eric Steven, Rheinbay, Esther, Lawrence, Michael, Cortes, Maria, Gabriel, Stacey, Golub, Todd, Getz, Gad Asher, Meyerson, Matthew L.
Other Authors: Broad Institute of MIT and Harvard
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/117280
https://orcid.org/0000-0002-5754-1719

Internet

http://hdl.handle.net/1721.1/117280
https://orcid.org/0000-0002-5754-1719

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