Regulation and Dysregulation of Chromosome Structure in Cancer
Cancer arises from genetic alterations that produce dysregulated gene expression programs. Normal gene regulation occurs in the context of chromosome loop structures called insulated neighborhoods, and recent studies have shown that these structures are altered and can contribute to oncogene dysregu...
Main Authors: | Hnisz, Denes, Schuijers, Jurian, Li, Charles Han, Young, Richard A. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
2018
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Online Access: | http://hdl.handle.net/1721.1/117286 https://orcid.org/0000-0001-8091-6112 https://orcid.org/0000-0001-8855-8647 |
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