Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis

Multiscale characterization of the mineral phase at skeletal sites of breast cancer metastasis

Skeletal metastases, the leading cause of death in advanced breast cancer patients, depend on tumor cell interactions with the mineralized bone extracellular matrix. Bone mineral is largely composed of hydroxyapatite (HA) nanocrystals with physicochemical properties that vary significantly by anatom...

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Bibliographic Details
Main Authors: He, Frank, Chiou, Aaron E., Loh, Hyun Chae, Lynch, Maureen, Seo, Bo Ri, Song, Young Hye, Lee, Min Joon, Hoerth, Rebecca, Bortel, Emely L., Willie, Bettina M., Duda, Georg N., Estroff, Lara A., Masic, Admir, Wagermaier, Wolfgang, Fratzl, Peter, Fischbach, Claudia
Other Authors: Massachusetts Institute of Technology. Department of Civil and Environmental Engineering
Format: Article
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/117406
https://orcid.org/0000-0001-6026-3433
https://orcid.org/0000-0002-1207-4926

Internet

http://hdl.handle.net/1721.1/117406
https://orcid.org/0000-0001-6026-3433
https://orcid.org/0000-0002-1207-4926

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