Correcting for batch effects in case-control microbiome studies

High-throughput data generation platforms, like mass-spectrometry, microarrays, and second-generation sequencing are susceptible to batch effects due to run-to-run variation in reagents, equipment, protocols, or personnel. Currently, batch correction methods are not commonly applied to microbiome se...

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Bibliographic Details
Main Authors: Gibbons, Sean Michael, Duvallet, Claire, Alm, Eric J
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Public Library of Science (PLoS) 2018
Online Access:http://hdl.handle.net/1721.1/117510
https://orcid.org/0000-0002-8093-8394
https://orcid.org/0000-0001-8294-9364