Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery

Cell-penetrating peptides (CPPs) can facilitate the intracellular delivery of large therapeutically relevant molecules, including proteins and oligonucleotides. Although hundreds of CPP sequences are described in the literature, predicting efficacious sequences remains difficult. Here, we focus spec...

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Bibliographic Details
Main Authors: Yao, Monica, Hanson, Gunnar J., Wolfe, Justin, Fadzen, Colin M., Choo, Zi-Ning, Holden, Rebecca Lynn, Pentelute, Bradley L.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Published: American Chemical Society (ACS) 2018
Online Access:http://hdl.handle.net/1721.1/117538
https://orcid.org/0000-0002-1003-6045
https://orcid.org/0000-0002-4139-9578
https://orcid.org/0000-0001-5286-4060