Understanding and Sensitizing Density-Dependent Persistence to Quinolone Antibiotics
Physiologic and environmental factors can modulate antibiotic activity and thus pose a significant challenge to antibiotic treatment. The quinolone class of antibiotics, which targets bacterial topoisomerases, fails to kill bacteria that have grown to high density; however, the mechanistic basis for...
| Main Authors: | , , , , , |
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| Format: | Article |
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Elsevier BV
2018
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| Online Access: | http://hdl.handle.net/1721.1/117581 https://orcid.org/0000-0002-9512-0659 https://orcid.org/0000-0002-0712-3383 https://orcid.org/0000-0002-5560-8246 |