A CRISPR–Cas9-based gene drive platform for genetic interaction analysis in Candida albicans
Candida albicans is the leading cause of fungal infections; yet, complex genetic interaction analysis remains cumbersome in this diploid pathogen. Here, we developed a CRISPR-Cas9-based 'gene drive array' platform to facilitate efficient genetic analysis in C. albicans. In our system, a mo...
Main Authors: | , , , , , , , , , , , , |
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Other Authors: | |
Format: | Article |
Published: |
Nature Publishing Group
2018
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Online Access: | http://hdl.handle.net/1721.1/117583 |