A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties

Distant metastasis is the major cause of breast cancer-related mortality, commonly emerging clinically after 5 or more years of seeming 'cure'of the primary tumor, indicating a quiescent dormancy. The lack of relevant accessible model systems for metastasis that recreate this latent stage...

Full description

Bibliographic Details
Main Authors: Wheeler, S. E., Stolz, D. B., Venkataramanan, R., Wells, A., Shepard, Nieman J., Clark, Abigail M, Young, Carissa L., Stockdale, Linda, Zhao, Weian, Lauffenburger, Douglas A, Griffith, Linda G
Other Authors: Massachusetts Institute of Technology. Biotechnology Process Engineering Center
Format: Article
Published: Royal Society of Chemistry (RSC) 2018
Online Access:http://hdl.handle.net/1721.1/117603
https://orcid.org/0000-0002-8581-1261
https://orcid.org/0000-0002-0050-989X
https://orcid.org/0000-0002-1801-5548