A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties
Distant metastasis is the major cause of breast cancer-related mortality, commonly emerging clinically after 5 or more years of seeming 'cure'of the primary tumor, indicating a quiescent dormancy. The lack of relevant accessible model systems for metastasis that recreate this latent stage...
Main Authors: | Wheeler, S. E., Stolz, D. B., Venkataramanan, R., Wells, A., Shepard, Nieman J., Clark, Abigail M, Young, Carissa L., Stockdale, Linda, Zhao, Weian, Lauffenburger, Douglas A, Griffith, Linda G |
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Other Authors: | Massachusetts Institute of Technology. Biotechnology Process Engineering Center |
Format: | Article |
Published: |
Royal Society of Chemistry (RSC)
2018
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Online Access: | http://hdl.handle.net/1721.1/117603 https://orcid.org/0000-0002-8581-1261 https://orcid.org/0000-0002-0050-989X https://orcid.org/0000-0002-1801-5548 |
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