Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies

Microphysiological systems (MPS), consisting of tissue constructs, biomaterials, and culture media, aim to recapitulate relevant organ functions in vitro. MPS components are housed in fluidic hardware with operational protocols, such as periodic complete media replacement. Such batch-like operations...

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Bibliographic Details
Main Authors: Dallas, Matthew, Stokes, Cynthia L., Maass, Christian Alexander, LaBarge, Matthew E, Shockley, Michael J, Valdez Macias, Jorge Luis, Geishecker, Emily R, Griffith, Linda G, Cirit, Murat
Other Authors: Massachusetts Institute of Technology. Biotechnology Process Engineering Center
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/117618
https://orcid.org/0000-0002-6673-087X
https://orcid.org/0000-0002-1801-5548