Establishing quasi-steady state operations of microphysiological systems (MPS) using tissue-specific metabolic dependencies
Microphysiological systems (MPS), consisting of tissue constructs, biomaterials, and culture media, aim to recapitulate relevant organ functions in vitro. MPS components are housed in fluidic hardware with operational protocols, such as periodic complete media replacement. Such batch-like operations...
Main Authors: | Dallas, Matthew, Stokes, Cynthia L., Maass, Christian Alexander, LaBarge, Matthew E, Shockley, Michael J, Valdez Macias, Jorge Luis, Geishecker, Emily R, Griffith, Linda G, Cirit, Murat |
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Other Authors: | Massachusetts Institute of Technology. Biotechnology Process Engineering Center |
Format: | Article |
Published: |
Nature Publishing Group
2018
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Online Access: | http://hdl.handle.net/1721.1/117618 https://orcid.org/0000-0002-6673-087X https://orcid.org/0000-0002-1801-5548 |
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