ADAM10 Sheddase Activity is a Potential Lung-Cancer Biomarker

Background: Increases in expression of ADAM10 and ADAM17 genes and proteins are inconsistently found in cancer lesions, and are not validated as clinically useful biomarkers. The enzyme-specific proteolytic activities, which are solely mediated by the active mature enzymes, directly reflect enzyme c...

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Bibliographic Details
Main Authors: Yoneyama, Toshie, Gorry, Michael, Sobo-Vujanovic, Andrea, Lin, Yan, Vujanovic, Lazar, Gaither-Davis, Autumn, Moss, Marcia L., Stabile, Laura P., Herman, James, Vujanovic, Nikola L., Miller, Miles Aaron, Griffith, Linda G, Lauffenburger, Douglas A
Other Authors: Massachusetts Institute of Technology. Biotechnology Process Engineering Center
Format: Article
Published: Ivyspring International Publisher 2018
Online Access:http://hdl.handle.net/1721.1/117640
https://orcid.org/0000-0002-1801-5548
https://orcid.org/0000-0002-0050-989X