N-methyl d-Aspartate Channels Link Ammonia and Epithelial Cell Death Mechanisms in Helicobacter pylori Infection

N-methyl d-Aspartate Channels Link Ammonia and Epithelial Cell Death Mechanisms in Helicobacter pylori Infection

Background & Aims: Helicobacter pylori infection is a risk factor for gastric cancer. Ammonia/ammonium (A/A) is a cytotoxin generated by H pylori that kills gastric epithelial cells. We investigated whether A/A cytotoxicity occurs by activating N-methyl d-aspartate (NMDA) channels, which results...

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Bibliographic Details
Main Authors: Seo, Ji Hye, Peek, Richard M., Hagen, Susan J., Fox, James G
Other Authors: Massachusetts Institute of Technology. Division of Comparative Medicine
Format: Article
Published: Elsevier BV 2018
Online Access:http://hdl.handle.net/1721.1/117648
https://orcid.org/0000-0001-9307-6116

Internet

http://hdl.handle.net/1721.1/117648
https://orcid.org/0000-0001-9307-6116

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