Commensal microflora-induced T cell responses mediate progressive neurodegeneration in glaucoma

Commensal microflora-induced T cell responses mediate progressive neurodegeneration in glaucoma

Glaucoma is the most prevalent neurodegenerative disease and a leading cause of blindness worldwide. The mechanisms causing glaucomatous neurodegeneration are not fully understood. Here we show, using mice deficient in T and/or B cells and adoptive cell transfer, that transient elevation of intraocu...

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Bibliographic Details
Main Authors: Chen, Huihui, Cho, Kin-Sang, Vu, T. H. Khanh, Chen, Guochun, Mathew, Rose, McHam, M. Lisa, Fazelat, Ahad, Lashkari, Kameran, AU, Ngan Pan Bennett, TSE, Joyce Ka Yu, Li, Yingqian, Yu, Honghua, Yang, Lanbo, Stein-Streilein, Joan, Ma, Chi Him Eddie, Woolf, Clifford J., Jager, Martine J., Chen, Jianzhu, Chen, Dong F., Shen, Chase, Kaur, Mandeep, Fox, James G, Whary, Mark T.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/117669
https://orcid.org/0000-0001-9816-2187
https://orcid.org/0000-0001-9307-6116

Internet

http://hdl.handle.net/1721.1/117669
https://orcid.org/0000-0001-9816-2187
https://orcid.org/0000-0001-9307-6116

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