Profiling drugs for rheumatoid arthritis that inhibit synovial fibroblast activation

Activation of synovial fibroblasts (SFs) contributes to rheumatoid arthritis (RA) by damaging synovial membranes and generating inflammatory cytokines that recruit immune cells to the joint. In this paper we profile cytokine secretion by primary human SFs from healthy tissues and from donors with RA...

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Bibliographic Details
Main Authors: Jenney, Anne P, Swantek, Jennifer L, Burke, John M, Sorger, Peter K, Jones II, Douglas S., Lauffenburger, Douglas A
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Springer Nature 2018
Online Access:http://hdl.handle.net/1721.1/117697
https://orcid.org/0000-0002-0050-989X