Exploiting glycan topography for computational design of Env glycoprotein antigenicity

Exploiting glycan topography for computational design of Env glycoprotein antigenicity

Mounting evidence suggests that glycans, rather than merely serving as a “shield”, contribute critically to antigenicity of the HIV envelope (Env) glycoprotein, representing critical antigenic determinants for many broadly neutralizing antibodies (bNAbs). While many studies have focused on defining...

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Bibliographic Details
Main Authors: Zhao, Peng, Draghi, Monia, Arevalo, Claudia, Karsten, Christina B., Suscovich, Todd J., Gunn, Bronwyn, Streeck, Hendrik, Brass, Abraham L., Tiemeyer, Michael, Seaman, Michael, Mascola, John R., Wells, Lance, Alter, Galit, Yu, Wen-Han, Lauffenburger, Douglas A
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: Public Library of Science 2018
Online Access:http://hdl.handle.net/1721.1/117701
https://orcid.org/0000-0002-0050-989X

Internet

http://hdl.handle.net/1721.1/117701
https://orcid.org/0000-0002-0050-989X

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