Normal aging induces A1-like astrocyte reactivity

The decline of cognitive function occurs with aging, but the mechanisms responsible are unknown. Astrocytes instruct the formation, maturation, and elimination of synapses, and impairment of these functions has been implicated in many diseases. These findings raise the question of whether astrocyte...

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Bibliographic Details
Main Authors: Clarke, Laura E., Liddelow, Shane A., Chakraborty, Chandrani, Münch, Alexandra E., Heiman, Myriam, Barres, Ben A.
Other Authors: Massachusetts Institute of Technology. Department of Brain and Cognitive Sciences
Format: Article
Published: Proceedings of the National Academy of Sciences 2018
Online Access:http://hdl.handle.net/1721.1/117720
https://orcid.org/0000-0002-6365-8673