Quantitative Phosphoproteomics Reveals Wee1 Kinase as a Therapeutic Target in a Model of Proneural Glioblastoma

Glioblastoma (GBM) is the most common malignant primary brain cancer. With a median survival of about a year, new approaches to treating this disease are necessary. To identify signaling molecules regulating GBM progression in a genetically engineered murine model of proneural GBM, we quantified pho...

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Bibliographic Details
Main Authors: Lei, Liang, Bakken, Katrina K., Sims, Peter A., Sarkaria, Jann N., Canoll, Peter, Lescarbeau, Rebecca S., White, Forest M.
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: American Association for Cancer Research (AACR) 2018
Online Access:http://hdl.handle.net/1721.1/117725
https://orcid.org/0000-0003-2409-4315
https://orcid.org/0000-0002-1545-1651