Quantitative Phosphoproteomics Reveals Wee1 Kinase as a Therapeutic Target in a Model of Proneural Glioblastoma
Glioblastoma (GBM) is the most common malignant primary brain cancer. With a median survival of about a year, new approaches to treating this disease are necessary. To identify signaling molecules regulating GBM progression in a genetically engineered murine model of proneural GBM, we quantified pho...
Main Authors: | Lei, Liang, Bakken, Katrina K., Sims, Peter A., Sarkaria, Jann N., Canoll, Peter, Lescarbeau, Rebecca S., White, Forest M. |
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Other Authors: | Massachusetts Institute of Technology. Department of Biological Engineering |
Format: | Article |
Published: |
American Association for Cancer Research (AACR)
2018
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Online Access: | http://hdl.handle.net/1721.1/117725 https://orcid.org/0000-0003-2409-4315 https://orcid.org/0000-0002-1545-1651 |
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