A mixed antagonistic/synergistic miRNA repression model enables accurate predictions of multi-input miRNA sensor activity
MicroRNAs (miRNAs) regulate a majority of protein-coding genes, affecting nearly all biological pathways. However, the quantitative dimensions of miRNA-based regulation are not fully understood. In particular, the implications of miRNA target site location, composition rules for multiple target site...
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Format: | Article |
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Nature Publishing Group
2018
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Online Access: | http://hdl.handle.net/1721.1/117727 https://orcid.org/0000-0003-4600-0383 https://orcid.org/0000-0003-0396-2443 |