Network analysis identifies chromosome intermingling regions as regulatory hotspots for transcription

The 3D structure of the genome plays a key role in regulatory control of the cell. Experimental methods such as high-throughput chromosome conformation capture (Hi-C) have been developed to probe the 3D structure of the genome. However, it remains a challenge to deduce from these data chromosome reg...

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Bibliographic Details
Main Authors: Belyaeva, Anastasiya, Venkatachalapathy, Saradha, Nagarajan, Mallika, Shivashankar, G. V., Uhler, Caroline
Other Authors: Massachusetts Institute of Technology. Institute for Data, Systems, and Society
Format: Article
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/117732
https://orcid.org/0000-0001-7364-1149