Local regulation of gene expression by lncRNA promoters, transcription and splicing

Mammalian genomes are pervasively transcribed to produce thousands of long non-coding RNAs (lncRNAs). A few of these lncRNAs have been shown to recruit regulatory complexes through RNA–protein interactions to influence the expression of nearby genes, and it has been suggested that many other lncRNAs...

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Bibliographic Details
Main Authors: Haines, Jenna E., Perez, Elizabeth M., Munson, Glen, Kane, Michael, McDonel, Patrick E., Guttman, Mitchell, Engreitz, Jesse Michael, Chen, Jennifer, Lander, Eric Steven
Other Authors: Institute for Medical Engineering and Science
Format: Article
Language:en_US
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/117775
https://orcid.org/0000-0002-5754-1719
https://orcid.org/0000-0002-6664-2597