Cost-effective high-throughput single-haplotype iterative mapping and sequencing for complex genomic structures

The reference sequences of structurally complex regions can be obtained only through highly accurate clone-based approaches. We and others have successfully used single-haplotype iterative mapping and sequencing (SHIMS) 1.0 to assemble structurally complex regions across the sex chromosomes of sever...

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Bibliographic Details
Main Authors: Bellott, Daniel W, Cho, Ting-Jan, Hughes, Jennifer F, Skaletsky, Helen, Page, David C
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/118374
https://orcid.org/0000-0001-9920-3411