Engineering circular RNA for potent and stable translation in eukaryotic cells
Messenger RNA (mRNA) has broad potential for application in biological systems. However, one fundamental limitation to its use is its relatively short half-life in biological systems. Here we develop exogenous circular RNA (circRNA) to extend the duration of protein expression from full-length RNA m...
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| Format: | Article |
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Nature Publishing Group
2018
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| Online Access: | http://hdl.handle.net/1721.1/118414 https://orcid.org/0000-0003-4617-8157 https://orcid.org/0000-0001-8607-0189 https://orcid.org/0000-0001-5629-4798 |