Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR–mediated direct in vivo screening

Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR–mediated direct in vivo screening

Cancer genomics consortia have charted the landscapes of numerous human cancers. Whereas somemutations were found in classical oncogenes and tumor suppressors, others have not yet been functionally studied in vivo. To date, a comprehensive assessment of how these genes influence oncogenesis is lacki...

Fuld beskrivelse

Bibliografiske detaljer
Main Authors: Wang, Guangchuan, Chow, Ryan D., Ye, Lupeng, Guzman, Christopher D., Dai, Xiaoyun, Dong, Matthew B., Zhang, Feng, Platt, Randall Jeffrey, Chen, Sidi, Sharp, Phillip A.
Andre forfattere: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Udgivet: American Association for the Advancement of Science (AAAS) 2018
Online adgang:http://hdl.handle.net/1721.1/118426
https://orcid.org/0000-0003-2782-2509
https://orcid.org/0000-0003-1465-1691

Internet

http://hdl.handle.net/1721.1/118426
https://orcid.org/0000-0003-2782-2509
https://orcid.org/0000-0003-1465-1691

Lignende værker