BET bromodomain proteins regulate enhancer function during adipogenesis

Developmental transitions are guided by master regulatory transcription factors. During adipogenesis, a transcriptional cascade culminates in the expression of PPARγ and C/EBPα, which orchestrate activation of the adipocyte gene expression program. However, the coactivators controlling PPARγ and C/E...

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Bibliografiska uppgifter
Huvudupphovsmän: Brown, Jonathan D., Feldman, Zachary B., Doherty, Sean P., Reyes, Jaime M., Rahl, Peter B., Lin, Charles Y., Sheng, Quanhu, Duan, Qiong, Federation, Alexander J., Kung, Andrew L., Haldar, Saptarsi M., Plutzky, Jorge, Bradner, James E., Young, Richard A.
Övriga upphovsmän: Massachusetts Institute of Technology. Department of Biology
Materialtyp: Artikel
Publicerad: National Academy of Sciences (U.S.) 2018
Länkar:http://hdl.handle.net/1721.1/118467
https://orcid.org/0000-0001-8855-8647