BET bromodomain proteins regulate enhancer function during adipogenesis

BET bromodomain proteins regulate enhancer function during adipogenesis

Developmental transitions are guided by master regulatory transcription factors. During adipogenesis, a transcriptional cascade culminates in the expression of PPARγ and C/EBPα, which orchestrate activation of the adipocyte gene expression program. However, the coactivators controlling PPARγ and C/E...

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Bibliographic Details
Main Authors: Brown, Jonathan D., Feldman, Zachary B., Doherty, Sean P., Reyes, Jaime M., Rahl, Peter B., Lin, Charles Y., Sheng, Quanhu, Duan, Qiong, Federation, Alexander J., Kung, Andrew L., Haldar, Saptarsi M., Plutzky, Jorge, Bradner, James E., Young, Richard A.
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/118467
https://orcid.org/0000-0001-8855-8647

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