Computational modeling of three-dimensional ECM-rigidity sensing to guide directed cell migration

Computational modeling of three-dimensional ECM-rigidity sensing to guide directed cell migration

Filopodia have a key role in sensing both chemical and mechanical cues in surrounding extracellular matrix (ECM). However, quantitative understanding is still missing in the filopodialmechanosensing of local ECM stiffness, resulting from dynamic interactions between filopodia and the surrounding 3D...

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Bibliographic Details
Main Authors: Silberberg, Yaron R., Kim, Min-Cheol, Abeyaratne, Rohan, Kamm, Roger Dale, Asada, Haruhiko
Other Authors: Massachusetts Institute of Technology. Department of Biological Engineering
Format: Article
Published: National Academy of Sciences (U.S.) 2018
Online Access:http://hdl.handle.net/1721.1/118468
https://orcid.org/0000-0001-6649-9463
https://orcid.org/0000-0003-2912-1538
https://orcid.org/0000-0002-7232-304X
https://orcid.org/0000-0003-3155-6223

Internet

http://hdl.handle.net/1721.1/118468
https://orcid.org/0000-0001-6649-9463
https://orcid.org/0000-0003-2912-1538
https://orcid.org/0000-0002-7232-304X
https://orcid.org/0000-0003-3155-6223

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