Computational modeling of three-dimensional ECM-rigidity sensing to guide directed cell migration
Filopodia have a key role in sensing both chemical and mechanical cues in surrounding extracellular matrix (ECM). However, quantitative understanding is still missing in the filopodialmechanosensing of local ECM stiffness, resulting from dynamic interactions between filopodia and the surrounding 3D...
| Main Authors: | , , , , |
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| Format: | Article |
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National Academy of Sciences (U.S.)
2018
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| Online Access: | http://hdl.handle.net/1721.1/118468 https://orcid.org/0000-0001-6649-9463 https://orcid.org/0000-0003-2912-1538 https://orcid.org/0000-0002-7232-304X https://orcid.org/0000-0003-3155-6223 |