Establishment of human pluripotent stem cell-derived pancreatic β-like cells in the mouse pancreas
Type 1 diabetes is characterized by autoimmune destruction of β cells located in pancreatic islets. However, tractable in vivo models of human pancreatic β cells have been limited. Here, we generated xenogeneic human pancreatic β-like cells in the mouse pancreas by orthotopic transplantation of stem...
Main Authors: | , , , , |
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Other Authors: | |
Format: | Article |
Published: |
National Academy of Sciences (U.S.)
2018
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Online Access: | http://hdl.handle.net/1721.1/118469 |