The Dopamine Transporter Recycles via a Retromer-Dependent Postendocytic Mechanism: Tracking Studies Using a Novel Fluorophore-Coupling Approach

Presynaptic reuptake, mediated by the dopamine (DA) transporter (DAT), terminates DAergic neurotransmission and constrains extracellular DA levels. Addictive and therapeutic psychostimulants inhibit DA reuptake and multiple DAT coding variants have been reported in patients with neuropsychiatric dis...

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Bibliographic Details
Main Authors: Wu, Sijia, Fagan, Rita R., Uttamapinant, Chayasith, Lifshitz, Lawrence M., Fogarty, Kevin E., Ting, Alice Y., Melikian, Haley E.
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Published: Society for Neuroscience 2018
Online Access:http://hdl.handle.net/1721.1/118614