The Dopamine Transporter Recycles via a Retromer-Dependent Postendocytic Mechanism: Tracking Studies Using a Novel Fluorophore-Coupling Approach
Presynaptic reuptake, mediated by the dopamine (DA) transporter (DAT), terminates DAergic neurotransmission and constrains extracellular DA levels. Addictive and therapeutic psychostimulants inhibit DA reuptake and multiple DAT coding variants have been reported in patients with neuropsychiatric dis...
Main Authors: | Wu, Sijia, Fagan, Rita R., Uttamapinant, Chayasith, Lifshitz, Lawrence M., Fogarty, Kevin E., Ting, Alice Y., Melikian, Haley E. |
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Other Authors: | Massachusetts Institute of Technology. Department of Chemistry |
Format: | Article |
Published: |
Society for Neuroscience
2018
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Online Access: | http://hdl.handle.net/1721.1/118614 |
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