Metagenomic mining of regulatory elements enables programmable species-selective gene expression

Metagenomic mining of regulatory elements enables programmable species-selective gene expression

Robust and predictably performing synthetic circuits rely on the use of well-characterized regulatory parts across different genetic backgrounds and environmental contexts. Here we report the large-scale metagenomic mining of thousands of natural 5′ regulatory sequences from diverse bacteria, and th...

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Bibliographic Details
Main Authors: Johns, Nathan I, Yim, Sung Sun, Blazejewski, Tomasz, Dias Gomes, Antonio, Yang, Anthony, Smillie, Chris S, Smith, Mark Burnham, Alm, Eric J, Kosuri, Sriram, Wang, Harris H
Other Authors: Institute for Medical Engineering and Science
Format: Article
Published: Springer Nature 2018
Online Access:http://hdl.handle.net/1721.1/118647
https://orcid.org/0000-0002-8202-5222
https://orcid.org/0000-0003-4700-5987
https://orcid.org/0000-0001-8294-9364
https://orcid.org/0000-0002-4661-0600

Internet

http://hdl.handle.net/1721.1/118647
https://orcid.org/0000-0002-8202-5222
https://orcid.org/0000-0003-4700-5987
https://orcid.org/0000-0001-8294-9364
https://orcid.org/0000-0002-4661-0600

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