Synthesizing Signaling Pathways from Temporal Phosphoproteomic Data

Synthesizing Signaling Pathways from Temporal Phosphoproteomic Data

We present a method for automatically discovering signaling pathways from time-resolved phosphoproteomic data. The Temporal Pathway Synthesizer (TPS) algorithm uses constraint-solving techniques first developed in the context of formal verification to explore paths in an interaction network. It syst...

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Bibliographic Details
Main Authors: Köksal, Ali Sinan, Beck, Kirsten, Cronin, Dylan R., Camp, Nathan D., MacGilvray, Matthew E., Bodík, Rastislav, Fisher, Jasmin, McKenna, Aaron, Srivastava, Saurabh, Wolf Yadlin, Alejandro Marcelo, Fraenkel, Ernest, Gitter, Anthony
Other Authors: Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory
Format: Article
Published: Elsevier 2018
Online Access:http://hdl.handle.net/1721.1/118655
https://orcid.org/0000-0001-9249-8181
https://orcid.org/0000-0002-5324-9833

Internet

http://hdl.handle.net/1721.1/118655
https://orcid.org/0000-0001-9249-8181
https://orcid.org/0000-0002-5324-9833

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