Synthesizing Signaling Pathways from Temporal Phosphoproteomic Data
We present a method for automatically discovering signaling pathways from time-resolved phosphoproteomic data. The Temporal Pathway Synthesizer (TPS) algorithm uses constraint-solving techniques first developed in the context of formal verification to explore paths in an interaction network. It syst...
Main Authors: | Köksal, Ali Sinan, Beck, Kirsten, Cronin, Dylan R., Camp, Nathan D., MacGilvray, Matthew E., Bodík, Rastislav, Fisher, Jasmin, McKenna, Aaron, Srivastava, Saurabh, Wolf Yadlin, Alejandro Marcelo, Fraenkel, Ernest, Gitter, Anthony |
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Other Authors: | Massachusetts Institute of Technology. Computer Science and Artificial Intelligence Laboratory |
Format: | Article |
Published: |
Elsevier
2018
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Online Access: | http://hdl.handle.net/1721.1/118655 https://orcid.org/0000-0001-9249-8181 https://orcid.org/0000-0002-5324-9833 |
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