Long-term viability and function of transplanted islets macroencapsulated at high density are achieved by enhanced oxygen supply

Transplantation of encapsulated islets can cure diabetes without immunosuppression, but oxygen supply limitations can cause failure. We investigated a retrievable macroencapsulation device wherein islets are encapsulated in a planar alginate slab and supplied with exogenous oxygen from a replenishab...

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Bibliographic Details
Main Authors: Evron, Yoav, Colton, Clark K., Ludwig, Barbara, Weir, Gordon C., Zimermann, Baruch, Maimon, Shiri, Neufeld, Tova, Shalev, Nurit, Goldman, Tali, Leon, Assaf, Yavriyants, Karina, Shabtay, Noa, Rozenshtein, Tania, Azarov, Dimitri, DiIenno, Amanda R., Steffen, Anja, de Vos, Paul, Bornstein, Stefan R., Barkai, Uriel, Rotem, Avi, Colton, Clark K, DiIenno, Amanda Rose
Other Authors: Massachusetts Institute of Technology. Department of Chemical Engineering
Format: Article
Published: Springer Nature 2018
Online Access:http://hdl.handle.net/1721.1/118745
https://orcid.org/0000-0001-8777-9632
https://orcid.org/0000-0002-4259-480X