Interaction of the New Monofunctional Anticancer Agent Phenanthriplatin With Transporters for Organic Cations

Cancer treatment with platinum compounds is an important achievement of modern chemotherapy. However, despite the beneficial effects, the clinical impact of these agents is hampered by the development of drug resistance as well as dose-limiting side effects. The efficacy but also side effects of pla...

Full description

Bibliographic Details
Main Authors: Hucke, Anna, Park, Ga Young, Bauer, Oliver B., Beyer, Georg, Köppen, Christina, Zeeh, Dorothea, Wehe, Christoph A., Sperling, Michael, Schröter, Rita, Kantauskaitè, Marta, Hagos, Yohannes, Karst, Uwe, Lippard, Stephen J., Ciarimboli, Giuliano
Other Authors: Massachusetts Institute of Technology. Department of Chemistry
Format: Article
Published: Frontiers Media S.A. 2018
Online Access:http://hdl.handle.net/1721.1/118800
https://orcid.org/0000-0002-2693-4982