Osteoblasts remotely supply lung tumors with cancer-promoting SiglecF

Bone has a well-established role in advanced cancer. It provides a supportive microenvironment for the growth of metastatic cells that escape the primary tumor, which ultimately leads to loss of bone mass. Engblom et al. show that bone may also contribute to early-stage tumorigenesis through a mecha...

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Bibliographic Details
Main Authors: Rickelt, Steffen, Hynes, Richard O
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:en_US
Published: American Association for the Advancement of Science (AAAS) 2018
Online Access:http://hdl.handle.net/1721.1/118804
https://orcid.org/0000-0002-5224-7764
https://orcid.org/0000-0001-7603-8396