Osteoblasts remotely supply lung tumors with cancer-promoting SiglecF
Bone has a well-established role in advanced cancer. It provides a supportive microenvironment for the growth of metastatic cells that escape the primary tumor, which ultimately leads to loss of bone mass. Engblom et al. show that bone may also contribute to early-stage tumorigenesis through a mecha...
Main Authors: | Rickelt, Steffen, Hynes, Richard O |
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Other Authors: | Massachusetts Institute of Technology. Department of Biology |
Format: | Article |
Language: | en_US |
Published: |
American Association for the Advancement of Science (AAAS)
2018
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Online Access: | http://hdl.handle.net/1721.1/118804 https://orcid.org/0000-0002-5224-7764 https://orcid.org/0000-0001-7603-8396 |
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