Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis

Aneuploid Cell Survival Relies upon Sphingolipid Homeostasis

Aneuploidy, a hallmark of cancer cells, poses an appealing opportunity for cancer treatment and prevention strategies. Using a cell-based screen to identify small molecules that could selectively kill aneuploid cells, we identified the compound N-[2hydroxy-1-(4-morpholinylmethyl)-2-phenylethyl]-deca...

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Bibliographic Details
Main Authors: Tang, Yun-Chi, Yuwen, Hui, Wang, Kaiying, Bruno, Peter M., Bullock, Kevin, Deik, Amy, Zhong, Na, Huang, Tao, Wang, Lan, Clish, Clary B., Hemann, Michael T., Santaguida, Stefano, Trakala, Marianna, Pfau, Sarah Jeanne, Amon, Angelika B
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: American Association for Cancer Research (AACR) 2018
Online Access:http://hdl.handle.net/1721.1/118830
https://orcid.org/0000-0002-1501-6190
https://orcid.org/0000-0002-4698-2746
https://orcid.org/0000-0001-9837-0314

Internet

http://hdl.handle.net/1721.1/118830
https://orcid.org/0000-0002-1501-6190
https://orcid.org/0000-0002-4698-2746
https://orcid.org/0000-0001-9837-0314

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