A robust cell culture system supporting the complete life cycle of hepatitis B virus

The discovery of sodium taurocholate cotransporting polypeptide (NTCP) as the hepatitis B virus (HBV) receptor enabled researchers to create hepatoma cell lines susceptible to HBV infection. Infection in current systems, however, is inefficient and virus fails to spread. Infection efficiency is enha...

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Bibliographic Details
Main Authors: Michailidis, Eleftherios, Pabon, Jonathan, Xiang, Kuanhui, Park, Paul, Ramanan, Vyas, Hoffmann, Hans-Heinrich, Schneider, William M., de Jong, Ype P., Shlomai, Amir, Rice, Charles M., Bhatia, Sangeeta N
Other Authors: Massachusetts Institute of Technology. Institute for Medical Engineering & Science
Format: Article
Published: Nature Publishing Group 2018
Online Access:http://hdl.handle.net/1721.1/118848
https://orcid.org/0000-0002-1293-2097