A robust cell culture system supporting the complete life cycle of hepatitis B virus
The discovery of sodium taurocholate cotransporting polypeptide (NTCP) as the hepatitis B virus (HBV) receptor enabled researchers to create hepatoma cell lines susceptible to HBV infection. Infection in current systems, however, is inefficient and virus fails to spread. Infection efficiency is enha...
Main Authors: | Michailidis, Eleftherios, Pabon, Jonathan, Xiang, Kuanhui, Park, Paul, Ramanan, Vyas, Hoffmann, Hans-Heinrich, Schneider, William M., de Jong, Ype P., Shlomai, Amir, Rice, Charles M., Bhatia, Sangeeta N |
---|---|
Other Authors: | Massachusetts Institute of Technology. Institute for Medical Engineering & Science |
Format: | Article |
Published: |
Nature Publishing Group
2018
|
Online Access: | http://hdl.handle.net/1721.1/118848 https://orcid.org/0000-0002-1293-2097 |
Similar Items
-
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
by: Schwartz, Robert E., et al.
Published: (2015) -
CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus
by: Shlomai, Amir, et al.
Published: (2017) -
Genomic profiling and perturbation of Hepatitis B virus infection
by: Ramanan, Vyas
Published: (2017) -
Viral genome imaging of hepatitis C virus to probe heterogeneous viral infection and responses to antiviral therapies
by: Luna, Joseph M., et al.
Published: (2017) -
Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes
by: Michailidis, Eleftherios, et al.
Published: (2021)