PKM2 is not required for pancreatic ductal adenocarcinoma

Background While most cancer cells preferentially express the M2 isoform of the glycolytic enzyme pyruvate kinase (PKM2), PKM2 is dispensable for tumor development in several mouse cancer models. PKM2 is expressed in human pancreatic cancer, and there have been conflicting reports o...

Full description

Bibliographic Details
Main Authors: Danai, Laura V, Di Vizio, Dolores, Hillis, Alissandra L., Lau, Allison N., Devoe, Camille X., Vander Heiden, Matthew G., Dayton, Talya Lucia
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Language:English
Published: BioMed Central Ltd 2018
Online Access:http://hdl.handle.net/1721.1/118876
https://orcid.org/0000-0003-4250-7355
https://orcid.org/0000-0002-7994-7963
https://orcid.org/0000-0002-6702-4192