Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota

Intestinal Epithelial Sirtuin 1 Regulates Intestinal Inflammation During Aging in Mice by Altering the Intestinal Microbiota

Intestinal epithelial homeostasis is maintained by complex interactions among epithelial cells, commensal gut microorganisms, and immune cells. Disruption of this homeostasis is associated with disorders such as inflammatory bowel disease (IBD), but the mechanisms of this process are not clear. We i...

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Bibliographic Details
Main Authors: Wellman, Alicia S., Metukuri, Mallikarjuna R., Kazgan, Nevzat, Xu, Xiaojiang, Xu, Qing, Ren, Natalie S.X., Shanahan, Michael T., Kang, Ashley, Chen, Willa, Azcarate-Peril, M. Andrea, Gulati, Ajay S., Fargo, David C., Li, Xiaoling, Guarente, Leonard Pershing, Czopik, Agnieszka
Other Authors: Massachusetts Institute of Technology. Department of Biology
Format: Article
Published: Elsevier BV 2018
Online Access:http://hdl.handle.net/1721.1/118956
https://orcid.org/0000-0003-4064-2510

Internet

http://hdl.handle.net/1721.1/118956
https://orcid.org/0000-0003-4064-2510

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